A woman with advanced ovarian cancer has become the first patient in the world to receive a pioneering new therapy, in what is being hailed as a "landmark moment".
Two of the High Speed 2 (HS2) railway's most significant private sector deals have been renegotiated, the government will announce on Friday, as it tries to demonstrate that Britain's biggest infrastructure white elephant is finally under control.
A Virgin Atlantic engineer died of a traumatic brain injury after an explosion as he worked inside a plane fuel tank, an inquest heard.
Gianni Infantino is rapidly losing support to remain as FIFA president, Sky News has learned, after European nations announced a World Cup boycott if he goes ahead with selling part of the tournament to private investors.
Labour grandee Harriet Harman has said Labour should ban men from running in its next leadership election.
Deaths in Britain linked to heat over May and June this year were almost double the entire figure for 2025, new data has revealed.
England international footballer Ivan Toney has been charged with assault at a Soho nightclub.
Newcastle United's Eddie Howe has left his job as head coach, Sky Sports understands.
I realise the World Cup is over and, more to the point, no-one particularly wants to hear any more about the Argentinian football team, but indulge me for a moment
A woman and her boyfriend have been jailed for life for murdering her two-year-old daughter after weeks of abuse.